Breath gas analysis
In the last few decades, the analysis of volatile organic compounds (VOCs) in exhaled air has been investigated and further developed as a promising approach for the identification of biomarkers for the diagnosis and monitoring of various diseases. One of the main advantages of this procedure is its non-invasive approach. This is especially important for populations such as children and the elderly, and for diseases whose current standard diagnoses use invasive techniques such as biopsies and bronchoscopies.
In cooperation with translational and clinical partners, we are investigating breath gas patterns using Proton-transfer-reaction mass spectrometry (PTR-MS) in the following application areas:
- for analysis and characterization of psychiatric disorders
- for screening of lung cancer and respiratory disorders
- for headspace analysis of cell cultur lines
- for skin gas analysis
- for investigation of VOC variability on various lifestyle factors
We offer topics for bachelor and master thesis projects for students of various engineering disciplines (e.g. biosystems engineering, molecular biosystems, medical systems engineering, engineering cybernetics etc.). If you are interested, please contact us by e-mail and provide the following information: short CV, transcript of academic records, areas of interest and desired starting date.
